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Atypical Endometriosis & Malignant Transformation


Did you know that there are some forms of endometriosis that are classified as atypical and may be considered as precursor lesions (precancerous)? 

How common are atypical lesions and will all of them undergo malignant transformation if left untreated?

Research is still limited, so we don’t really know for sure. However, for the question of prevalence, in one large meta-analysis, 8% of biopsied endometriotic growths were classified as atypical (Van Gorp et al, 2004).

More studies are needed (with better stratification), but preliminary reports like this at least suggest that atypical endometriotic lesions may be more common than previously thought.

Just more evidence that we need more research funding & more awareness about endometriosis, including atypical forms.

Click here to read more about atypical endometriosis and its association with malignant transformation.

Want to join us to fast-track the cure for endometriosis? Sign up here to learn how you can participate in the EndoMarch-sponsored CrowdSourcing For The Cure study.

1 comment

  1. Mia Evans 8 months ago April 24, 2023

    I never took into account the fact that there would be eight percent of biopsied endometriotic growth would be considered atypical after a large meta-analysis was done. I will share this information with my sister to help her realize that she might need help regarding the symptoms she is experiencing, especially she should be getting endometriosis care. And I think getting checked as soon as possible will be vital to keep the problem from getting worse which can definitely affect her daily life.


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